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2025-06-28

[Journal of Hepatology] Antibodies elicited by hepatitis E vaccination in humans confer cross-genus protection against rat hepatitis E virus

AbstractBackground & AimsPaslahepevirus balayani (bHEV), also known as hepatitis E virus (HEV), encompasses eight genotypes, five of which infect humans. Rats are natural reservoirs of Rocahepevirus ratti genotype 1 (HEV-r-1; rat HEV; rHEV), which has recently been implicated in viral hepatitis. Despite the antigenic divergence between bHEV and rHEV, studies on shared protective antibodies remain rare....

2025-06-12

[Science Translational Medicine] Targeted suppression of glioma by ultralow-dose X-ray-induced photodynamic therapy and gold-based nanoclusters in preclinical models

AbstractThe diffuse and infiltrative nature of high-grade gliomas poses ongoing challenges in treatment and management. Radiotherapy is an important glioma treatment, with a standard radiotherapy dose of 60 gray. However, high-dose radiotherapy is associated with radiation-induced side effects on normal tissue. Scintillator-mediated low-dose x-ray–induced photodynamic therapy using kilovoltage x-rays ...

2025-05-14

WHO Prequalifies China-Made HIV Urine Self-Test Kit Developed by Our School

An HIV urine self-test kit called the Human Immunodeficiency Virus (HIV) type-I urine antibody diagnostic kit (colloidal gold), co-developed by the school of public health, Xiamen University and Beijing Wantai Biological Pharmacy Enterprise, recently obtained the prequalification of medical products from the World Health Organization, known as WHO PQ.It is the world's first HIV urine self-test kit ...

2025-04-27

[Cancer Research] SLC3A2-Mediated Lysine Uptake by Cancer Cells Restricts T cell Activity in Hepatocellular Carcinoma

AbstractAbnormal amino acid metabolism supports cancer cell proliferation, invasion, and immune evasion in hepatocellular carcinoma (HCC). Previous research exploring amino acid metabolism in HCC has primarily focused on how metabolic reprogramming impacts tumor cells. Here, we focused on the role of amino acid metabolism dysregulation in the crosstalk between HCC and T cells. HCC cells disrupted lysine ...

2025-03-24

Respiratory Multipathogen Prediction and Early-warning Platform of Our School Has Been Launched, Successfully Integrated with DeepSeek R1

Multipathogen respiratory infections have emerged as a critical public health concern. Common respiratory pathogens—including influenza viruses, SARS-CoV-2 (COVID-19),Mycoplasma pneumoniae, respiratory syncytial virus (RSV), and rhinoviruses—circulate widely, particularly during autumn, winter, and seasonal transitions. Globally, the epidemiology of respiratory diseases is complex and dynamic, with ...

2025-03-21

Guangming Daily Reports Our School's Achievement: Xiamen University Team Deciphers Bacterial "Death Code"

This article is republished from Guangming Daily:Recently, Professor Xilin Zhao’s team from the School of Public Health at Xiamen University has made a groundbreaking breakthrough in the field of bacterial death and "anti-death" (resistance to death, hereafter referred to as "anti-death"). Their research findings, published in the top international academic journal Proceedings of the National Academy ...

2025-02-24

?Nasopharyngeal Cancer Early Diagnosis Kit Led by Xiamen University Selected as One of the China's Top 10 Pharmaceutical Biotechnology Advances in 2024

Recently, the results of China's Top 10 Pharmaceutical Biotechnology Advances in 2024 were announced in Xiamen. The P85-Ab Nasopharyngeal Cancer Early Diagnosis Kit—the EBV BNLF2b Antibody Detection Kit (Magnetic Microparticle Chemiluminescence), jointly developed by the Ningshao Xia’s team from Xiang An Biomedine Laboratory of Xiamen University, and WAITAl BioPharm, has been approved for mar...